Associations of FGF21 and GDF15 with mitochondrial dysfunction in children living with perinatally-a...
Associations of FGF21 and GDF15 with mitochondrial dysfunction in children living with perinatally-acquired HIV: A cross-sectional evaluation of pediatric AIDS clinical trials group 219/219C
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Pediatric HIV/AIDS Cohort Study , for the Pediatric HIV/AIDS Cohort Study , Gojanovich, Greg S , Jacobson, Denise L , Broadwell, Carly , Karalius, Brad , Kirmse, Brian , Geffner, Mitchell E , Jao, Jennifer , Van Dyke, Russell B , McFarland, Elizabeth J , Silio, Margarita , Crain, Marilyn and Gerschenson, Mariana
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
In persons living with HIV, mitochondrial disease (MD) is difficult to diagnose, as clinical signs are non-specific with inconsistent patterns. Fibroblast growth factor 21 (FGF21) and growth differentiation factor 15 (GDF15) are mitokines elevated in MD patients without HIV, and associated with cardiometabolic comorbidities in adults living with HI...
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Full title
Associations of FGF21 and GDF15 with mitochondrial dysfunction in children living with perinatally-acquired HIV: A cross-sectional evaluation of pediatric AIDS clinical trials group 219/219C
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TN_cdi_plos_journals_2615610729
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2615610729
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0261563