Evaluation of Xa inhibitors as potential inhibitors of the SARS-CoV-2 Mpro protease
Evaluation of Xa inhibitors as potential inhibitors of the SARS-CoV-2 Mpro protease
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Based on previous large-scale in silico screening several factor Xa inhibitors were proposed to potentially inhibit SARS-CoV-2 Mpro. In addition to their known anticoagulants activity this potential inhibition could have an additional therapeutic effect on patients with COVID-19 disease. In this study we examined the binding of the Apixaban, Betrix...
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Full title
Evaluation of Xa inhibitors as potential inhibitors of the SARS-CoV-2 Mpro protease
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TN_cdi_plos_journals_2618879255
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2618879255
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0262482
