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Decreased glutamate transport in acivicin resistant Leishmania tarentolae

Decreased glutamate transport in acivicin resistant Leishmania tarentolae

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2620112715

Decreased glutamate transport in acivicin resistant Leishmania tarentolae

About this item

Full title

Decreased glutamate transport in acivicin resistant Leishmania tarentolae

Publisher

United States: Public Library of Science

Journal title

PLoS neglected tropical diseases, 2021-12, Vol.15 (12), p.e0010046-e0010046

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Studies of drug resistance in the protozoan parasites of the genus
Leishmania
have been helpful in revealing biochemical pathways as potential drug targets. The chlorinated glutamine analogue acivicin has shown good activity against
Leishmania
cells and was shown to target several enzymes containing amidotransferase domains. We selected...

Alternative Titles

Full title

Decreased glutamate transport in acivicin resistant Leishmania tarentolae

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2620112715

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2620112715

Other Identifiers

ISSN

1935-2735,1935-2727

E-ISSN

1935-2735

DOI

10.1371/journal.pntd.0010046

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