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A genome-wide CRISPR/Cas9 gene knockout screen identifies immunoglobulin superfamily DCC subclass me...

A genome-wide CRISPR/Cas9 gene knockout screen identifies immunoglobulin superfamily DCC subclass me...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2620156021

A genome-wide CRISPR/Cas9 gene knockout screen identifies immunoglobulin superfamily DCC subclass member 4 as a key host factor that promotes influenza virus endocytosis

About this item

Full title

A genome-wide CRISPR/Cas9 gene knockout screen identifies immunoglobulin superfamily DCC subclass member 4 as a key host factor that promotes influenza virus endocytosis

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2021-12, Vol.17 (12), p.e1010141-e1010141

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Influenza virus infection is dependent on host cellular factors, and identification of these factors and their underlying mechanisms can provide important information for the development of strategies to inhibit viral infection. Here, we used a highly pathogenic H5N1 influenza virus to perform a genome-wide CRISPR/Cas9 gene knockout screen in human...

Alternative Titles

Full title

A genome-wide CRISPR/Cas9 gene knockout screen identifies immunoglobulin superfamily DCC subclass member 4 as a key host factor that promotes influenza virus endocytosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2620156021

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2620156021

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1010141

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