Synthesis and characterization of novel ssDNA X-aptamers targeting Growth Hormone Releasing Hormone...
Synthesis and characterization of novel ssDNA X-aptamers targeting Growth Hormone Releasing Hormone (GHRH)
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Growth Hormone Releasing Hormone (GHRH), 44 amino acids containing hypothalamic hormone, retains the biological activity by its first 29 amino acids. GHRH (NH2 1-29) peptide antagonists inhibit the growth of prostate, breast, ovarian, renal, gastric, pancreatic cancer in vitro and in vivo. Aptamers, single-strand RNA, or DNA oligonucleotides are ca...
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Full title
Synthesis and characterization of novel ssDNA X-aptamers targeting Growth Hormone Releasing Hormone (GHRH)
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TN_cdi_plos_journals_2621919737
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2621919737
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0260144
