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Reduced blood pressure in sickle cell disease is associated with decreased angiotensin converting en...

Reduced blood pressure in sickle cell disease is associated with decreased angiotensin converting en...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2625265588

Reduced blood pressure in sickle cell disease is associated with decreased angiotensin converting enzyme (ACE) activity and is not modulated by ACE inhibition

About this item

Full title

Reduced blood pressure in sickle cell disease is associated with decreased angiotensin converting enzyme (ACE) activity and is not modulated by ACE inhibition

Publisher

United States: Public Library of Science

Journal title

PloS one, 2022-02, Vol.17 (2), p.e0263424-e0263424

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Sickle cell disease (SCD) incurs vaso-occlusive episodes and organ damage, including nephropathy. Despite displaying characteristics of vascular dysfunction, SCD patients tend to present relatively lower systemic blood pressure (BP), via an unknown mechanism. We investigated associations between BP and renin-angiotensin-system (RAS) components in S...

Alternative Titles

Full title

Reduced blood pressure in sickle cell disease is associated with decreased angiotensin converting enzyme (ACE) activity and is not modulated by ACE inhibition

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2625265588

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2625265588

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0263424

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