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High-level carbapenem tolerance requires antibiotic-induced outer membrane modifications

High-level carbapenem tolerance requires antibiotic-induced outer membrane modifications

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2640117674

High-level carbapenem tolerance requires antibiotic-induced outer membrane modifications

About this item

Full title

High-level carbapenem tolerance requires antibiotic-induced outer membrane modifications

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2022-02, Vol.18 (2), p.e1010307-e1010307

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Antibiotic tolerance is an understudied potential contributor to antibiotic treatment failure and the emergence of multidrug-resistant bacteria. The molecular mechanisms governing tolerance remain poorly understood. A prominent type of β-lactam tolerance relies on the formation of cell wall-deficient spheroplasts, which maintain structural integrit...

Alternative Titles

Full title

High-level carbapenem tolerance requires antibiotic-induced outer membrane modifications

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2640117674

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2640117674

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1010307

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