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Vaccinia virus D10 has broad decapping activity that is regulated by mRNA splicing

Vaccinia virus D10 has broad decapping activity that is regulated by mRNA splicing

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2640117881

Vaccinia virus D10 has broad decapping activity that is regulated by mRNA splicing

About this item

Full title

Vaccinia virus D10 has broad decapping activity that is regulated by mRNA splicing

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2022-02, Vol.18 (2), p.e1010099

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The mRNA 5’ cap structure serves both to protect transcripts from degradation and promote their translation. Cap removal is thus an integral component of mRNA turnover that is carried out by cellular decapping enzymes, whose activity is tightly regulated and coupled to other stages of the mRNA decay pathway. The poxvirus vaccinia virus (VACV) encod...

Alternative Titles

Full title

Vaccinia virus D10 has broad decapping activity that is regulated by mRNA splicing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2640117881

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2640117881

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1010099

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