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Cooperativity of catalytic and lectin-like domain of Trypanosoma congolense trans-sialidase modulate...

Cooperativity of catalytic and lectin-like domain of Trypanosoma congolense trans-sialidase modulate...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2640118542

Cooperativity of catalytic and lectin-like domain of Trypanosoma congolense trans-sialidase modulates its catalytic activity

About this item

Full title

Cooperativity of catalytic and lectin-like domain of Trypanosoma congolense trans-sialidase modulates its catalytic activity

Publisher

United States: Public Library of Science

Journal title

PLoS neglected tropical diseases, 2022-02, Vol.16 (2), p.e0009585

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Trans-sialidases (TS) represent a multi-gene family of unusual enzymes, which catalyse the transfer of terminal sialic acids (Sia) from sialoglycoconjugates to terminal galactose or
N
-acetylgalactosamine residues of oligosaccharides without the requirement of CMP-Neu5Ac, the activated Sia used by typical sialyltransferases. Enzymes comprise...

Alternative Titles

Full title

Cooperativity of catalytic and lectin-like domain of Trypanosoma congolense trans-sialidase modulates its catalytic activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2640118542

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2640118542

Other Identifiers

ISSN

1935-2735,1935-2727

E-ISSN

1935-2735

DOI

10.1371/journal.pntd.0009585

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