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The mismatched nucleotides encoded in vaccinia virus flip-and-flop hairpin telomeres serve an essent...

The mismatched nucleotides encoded in vaccinia virus flip-and-flop hairpin telomeres serve an essent...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2651150413

The mismatched nucleotides encoded in vaccinia virus flip-and-flop hairpin telomeres serve an essential role in virion maturation

About this item

Full title

The mismatched nucleotides encoded in vaccinia virus flip-and-flop hairpin telomeres serve an essential role in virion maturation

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2022-03, Vol.18 (3), p.e1010392-e1010392

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Poxvirus genomes consist of a linear duplex DNA that ends in short inverted and complementary hairpin structures. These elements also encode loops and mismatches that likely serve a role in genome packaging and perhaps replication. We constructed mutant vaccinia viruses (VACV) where the native hairpins were replaced by altered forms and tested effe...

Alternative Titles

Full title

The mismatched nucleotides encoded in vaccinia virus flip-and-flop hairpin telomeres serve an essential role in virion maturation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2651150413

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2651150413

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1010392

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