The mTOR inhibitor Rapamycin protects from premature cellular senescence early after experimental ki...
The mTOR inhibitor Rapamycin protects from premature cellular senescence early after experimental kidney transplantation
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Full title
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Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Interstitial fibrosis and tubular atrophy, a major cause of kidney allograft dysfunction, has been linked to premature cellular senescence. The mTOR inhibitor Rapamycin protects from senescence in experimental models, but its antiproliferative properties have raised concern early after transplantation particularly at higher doses. Its effect on sen...
Alternative Titles
Full title
The mTOR inhibitor Rapamycin protects from premature cellular senescence early after experimental kidney transplantation
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Record Identifier
TN_cdi_plos_journals_2653253587
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2653253587
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0266319
