The TSP-1 domain of the matricellular protein CCN5 is essential for its nuclear localization and ant...
The TSP-1 domain of the matricellular protein CCN5 is essential for its nuclear localization and anti-fibrotic function
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United States: Public Library of Science
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English
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United States: Public Library of Science
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The matricellular protein CCN5 exerts anti-fibrotic activity in hearts partly by inducing reverse trans-differentiation of myofibroblasts (MyoFBs) to fibroblasts (FBs). CCN5 consists of three structural domains: an insulin-like growth factor binding protein (IGFBP), a von Willebrand factor type C (VWC), and a thrombospondin type 1 (TSP-1). In this...
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The TSP-1 domain of the matricellular protein CCN5 is essential for its nuclear localization and anti-fibrotic function
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TN_cdi_plos_journals_2656181157
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2656181157
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0267629