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Imaging the influence of peripheral TRPV1-signaling on cerebral nociceptive processing applying fMRI...

Imaging the influence of peripheral TRPV1-signaling on cerebral nociceptive processing applying fMRI...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2656779798

Imaging the influence of peripheral TRPV1-signaling on cerebral nociceptive processing applying fMRI-based graph theory in a resiniferatoxin rat model

About this item

Full title

Imaging the influence of peripheral TRPV1-signaling on cerebral nociceptive processing applying fMRI-based graph theory in a resiniferatoxin rat model

Publisher

United States: Public Library of Science

Journal title

PloS one, 2022-04, Vol.17 (4), p.e0266669

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Resiniferatoxin (RTX), an extract from the spurge plant Euphorbia resinifera, is a potent agonist of the transient receptor potential cation channel subfamily V member 1 (TRPV1), mainly expressed on peripheral nociceptors-a prerequisite for nociceptive heat perception. Systemic overdosing of RTX can be used to desensitize specifically TRPV1-express...

Alternative Titles

Full title

Imaging the influence of peripheral TRPV1-signaling on cerebral nociceptive processing applying fMRI-based graph theory in a resiniferatoxin rat model

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2656779798

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2656779798

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0266669

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