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Differential mitochondrial protein interaction profile between human translocator protein and its A1...

Differential mitochondrial protein interaction profile between human translocator protein and its A1...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2686209022

Differential mitochondrial protein interaction profile between human translocator protein and its A147T polymorphism variant

About this item

Full title

Differential mitochondrial protein interaction profile between human translocator protein and its A147T polymorphism variant

Publisher

United States: Public Library of Science

Journal title

PloS one, 2022-05, Vol.17 (5), p.e0254296-e0254296

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The translocator protein (TSPO) has been implicated in mitochondrial transmembrane cholesterol transport, brain inflammation, and other mitochondrial functions. It is upregulated in glial cells during neuroinflammation in Alzheimer's disease. High affinity TSPO imaging radioligands are utilized to visualize neuroinflammation. However, this is hampe...

Alternative Titles

Full title

Differential mitochondrial protein interaction profile between human translocator protein and its A147T polymorphism variant

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2686209022

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2686209022

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0254296

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