Use of antisense oligonucleotides to target Notch3 in skeletal cells
Use of antisense oligonucleotides to target Notch3 in skeletal cells
About this item
Full title
Author / Creator
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Notch receptors are determinants of cell fate and function, and play an important role in the regulation of bone development and skeletal remodeling. Lateral Meningocele Syndrome (LMS) is a monogenic disorder associated with
NOTCH3
pathogenic variants that result in the stabilization of NOTCH3 and a gain-of-function. LMS presents with neurolo...
Alternative Titles
Full title
Use of antisense oligonucleotides to target Notch3 in skeletal cells
Authors, Artists and Contributors
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TN_cdi_plos_journals_2686245629
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2686245629
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0268225
