Synthesis and biological evaluation of thiazolidine-2-thione derivatives as novel xanthine oxidase i...
Synthesis and biological evaluation of thiazolidine-2-thione derivatives as novel xanthine oxidase inhibitors
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Xanthine oxidase (XO) is a key enzyme in the generation and development of hyperuricemia. Thiazolidine-2-thione, a typical heterocyclic compound, have been widely used in the field of drug synthesis. In this study, a series of novel thiazolidine-2-thione derivatives were synthesized as XO inhibitors, and the XO inhibitory potencies of obtained comp...
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Full title
Synthesis and biological evaluation of thiazolidine-2-thione derivatives as novel xanthine oxidase inhibitors
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TN_cdi_plos_journals_2686248658
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2686248658
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0268531
