Nano-hydroxyapatite improves intestinal absorption of acetazolamide (BCS Class IV drug)–but how?
Nano-hydroxyapatite improves intestinal absorption of acetazolamide (BCS Class IV drug)–but how?
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United States: Public Library of Science
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English
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United States: Public Library of Science
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We earlier reported that coating poorly water-soluble drugs with nano-hydroxyapatite (nano-HAP) improves bioavailability after oral administration. In the present study, we coated BCS Class IV drug acetazolamide (AZ) with nano-HAP (AZ/HAP formulation), and investigated its bioavailability and nano-HAP’s role in promoting it.
We tested AZ bioavai...
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Full title
Nano-hydroxyapatite improves intestinal absorption of acetazolamide (BCS Class IV drug)–but how?
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TN_cdi_plos_journals_2686259094
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2686259094
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0268067
