A novel bioassay to detect Nociceptin/Orphanin FQ release from single human polymorphonuclear cells
A novel bioassay to detect Nociceptin/Orphanin FQ release from single human polymorphonuclear cells
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Author / Creator
Bird, M F , Hebbes, C P , Scott, S W M , Willets, J , Thompson, J P and Lambert, D G
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Nociceptin/Orphanin FQ (N/OFQ) is the endogenous opioid agonist for the N/OFQ receptor or NOP. This receptor system is involved in pain processing but also has a role in immune regulation. Indeed, polymorphonuclear cells (PMNs) express mRNA for N/OFQ precursor and are a potential source for circulating N/OFQ. Current measurements are based on ELISA...
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Full title
A novel bioassay to detect Nociceptin/Orphanin FQ release from single human polymorphonuclear cells
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Record Identifier
TN_cdi_plos_journals_2687677796
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2687677796
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0268868
