BR2 cell penetrating peptide effectively delivers anti-p21Ras scFv to tumor cells with ganglioside e...
BR2 cell penetrating peptide effectively delivers anti-p21Ras scFv to tumor cells with ganglioside expression for therapy of ras-driven tumor
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Author / Creator
Yu, Ting , Shi, Yingxian , Pan, Xinyan , Feng, Qiang , Wang, Peng , Song, Shuling , Yang, Lilin and Yang, Julun
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Cell membrane penetrating peptide BR2 can bind with ganglioside and introduce foreign drugs into tumor cells. In this study, we employed BR2 to carry the broad-spectrum anti-p21Ras scFv prepared in our laboratory into ganglioside expressing tumor cells for therapy of ras-driven tumors.
BR2-p21Ras scFv gene was cloned to prokaryotic expression ve...
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Full title
BR2 cell penetrating peptide effectively delivers anti-p21Ras scFv to tumor cells with ganglioside expression for therapy of ras-driven tumor
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Record Identifier
TN_cdi_plos_journals_2687691006
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2687691006
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0269084
