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Increased glucocorticoid metabolism in diabetic kidney disease

Increased glucocorticoid metabolism in diabetic kidney disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2687704773

Increased glucocorticoid metabolism in diabetic kidney disease

About this item

Full title

Increased glucocorticoid metabolism in diabetic kidney disease

Publisher

San Francisco: Public Library of Science

Journal title

PloS one, 2022-06, Vol.17 (6), p.e0269920-e0269920

Language

English

Formats

Publication information

Publisher

San Francisco: Public Library of Science

More information

Scope and Contents

Contents

Glomerular damage indicated by proteinuria is a main symptom in diabetic nephropathy. Mineralocorticoid receptor (MR) antagonists (MRAs) are beneficial irrespective of aldosterone availability. Thus, we hypothesized an alternatively activated MR to promote glomerular damage in proteinuric diabetic nephropathy. Specifically, we aimed first to demons...

Alternative Titles

Full title

Increased glucocorticoid metabolism in diabetic kidney disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2687704773

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2687704773

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0269920

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