Nucleocapsid mutations in SARS-CoV-2 augment replication and pathogenesis
Nucleocapsid mutations in SARS-CoV-2 augment replication and pathogenesis
About this item
Full title
Author / Creator
Johnson, Bryan A. , Zhou, Yiyang , Lokugamage, Kumari G. , Vu, Michelle N. , Bopp, Nathen , Crocquet-Valdes, Patricia A. , Kalveram, Birte , Schindewolf, Craig , Liu, Yang , Scharton, Dionna , Plante, Jessica A. , Xie, Xuping , Aguilar, Patricia , Weaver, Scott C. , Shi, Pei-Yong , Walker, David H. , Routh, Andrew L. , Plante, Kenneth S. and Menachery, Vineet D.
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
While SARS-CoV-2 continues to adapt for human infection and transmission, genetic variation outside of the spike gene remains largely unexplored. This study investigates a highly variable region at residues 203–205 in the SARS-CoV-2 nucleocapsid protein. Recreating a mutation found in the alpha and omicron variants in an early pandemic (WA-1) backg...
Alternative Titles
Full title
Nucleocapsid mutations in SARS-CoV-2 augment replication and pathogenesis
Authors, Artists and Contributors
Author / Creator
Zhou, Yiyang
Lokugamage, Kumari G.
Vu, Michelle N.
Bopp, Nathen
Crocquet-Valdes, Patricia A.
Kalveram, Birte
Schindewolf, Craig
Liu, Yang
Scharton, Dionna
Plante, Jessica A.
Xie, Xuping
Aguilar, Patricia
Weaver, Scott C.
Shi, Pei-Yong
Walker, David H.
Routh, Andrew L.
Plante, Kenneth S.
Menachery, Vineet D.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2690721960
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2690721960
Other Identifiers
ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1010627
