The matricellular protein CCN5 induces apoptosis in myofibroblasts through SMAD7-mediated inhibition...
The matricellular protein CCN5 induces apoptosis in myofibroblasts through SMAD7-mediated inhibition of NFκB
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San Francisco: Public Library of Science
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Language
English
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San Francisco: Public Library of Science
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We previously showed that the matricellular protein CCN5 reverses established cardiac fibrosis (CF) through inducing apoptosis in myofibroblasts (MyoFBs) but not in cardiomyocytes or fibroblasts (FBs). In this study, we set out to elucidate the molecular mechanisms underlying CCN5-mediated selective apoptosis of MyoFBs. We first observed that the a...
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The matricellular protein CCN5 induces apoptosis in myofibroblasts through SMAD7-mediated inhibition of NFκB
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TN_cdi_plos_journals_2697325083
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2697325083
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0269735
