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Widespread emergence of OmpK36 loop 3 insertions among multidrug-resistant clones of Klebsiella pneu...

Widespread emergence of OmpK36 loop 3 insertions among multidrug-resistant clones of Klebsiella pneu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2703164473

Widespread emergence of OmpK36 loop 3 insertions among multidrug-resistant clones of Klebsiella pneumoniae

About this item

Full title

Widespread emergence of OmpK36 loop 3 insertions among multidrug-resistant clones of Klebsiella pneumoniae

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2022-07, Vol.18 (7), p.e1010334

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Mutations in outer membrane porins act in synergy with carbapenemase enzymes to increase carbapenem resistance in the important nosocomial pathogen,
Klebsiella pneumoniae
(KP). A key example is a di-amino acid insertion, Glycine-Aspartate (GD), in the extracellular loop 3 (L3) region of OmpK36 which constricts the pore and restricts entry of...

Alternative Titles

Full title

Widespread emergence of OmpK36 loop 3 insertions among multidrug-resistant clones of Klebsiella pneumoniae

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2703164473

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2703164473

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1010334

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