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In vitro sepsis induces Nociceptin/Orphanin FQ receptor (NOP) expression in primary human vascular e...

In vitro sepsis induces Nociceptin/Orphanin FQ receptor (NOP) expression in primary human vascular e...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2714860325

In vitro sepsis induces Nociceptin/Orphanin FQ receptor (NOP) expression in primary human vascular endothelial but not smooth muscle cells

About this item

Full title

In vitro sepsis induces Nociceptin/Orphanin FQ receptor (NOP) expression in primary human vascular endothelial but not smooth muscle cells

Publisher

United States: Public Library of Science

Journal title

PloS one, 2022-09, Vol.17 (9), p.e0274080-e0274080

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Sepsis is a dysregulated host response to infection that can cause widespread effects on other organs including cardiovascular depression, hypotension and organ failure. The receptor for Nociceptin/Orphanin FQ (N/OFQ), NOP is expressed on immune cells and these cells can release the peptide. Exogenous N/OFQ can dilate blood vessels and this peptide...

Alternative Titles

Full title

In vitro sepsis induces Nociceptin/Orphanin FQ receptor (NOP) expression in primary human vascular endothelial but not smooth muscle cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2714860325

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2714860325

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0274080

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