Engineered peptide PLG0206 overcomes limitations of a challenging antimicrobial drug class
Engineered peptide PLG0206 overcomes limitations of a challenging antimicrobial drug class
About this item
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Author / Creator
Huang, David B , Brothers, Kimberly M , Mandell, Jonathan B , Taguchi, Masashi , Alexander, Peter G , Parker, Dana M , Shinabarger, Dean , Pillar, Chris , Morrissey, Ian , Hawser, Stephen , Ghahramani, Parviz , Dobbins, Despina , Pachuda, Nicholas , Montelaro, Ronald , Steckbeck, Jonathan D and Urish, Kenneth L
Publisher
San Francisco: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
San Francisco: Public Library of Science
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Scope and Contents
Contents
The absence of novel antibiotics for drug-resistant and biofilm-associated infections is a global public health crisis. Antimicrobial peptides explored to address this need have encountered significant development challenges associated with size, toxicity, safety profile, and pharmacokinetics. We designed PLG0206, an engineered antimicrobial peptid...
Alternative Titles
Full title
Engineered peptide PLG0206 overcomes limitations of a challenging antimicrobial drug class
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Record Identifier
TN_cdi_plos_journals_2715088691
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2715088691
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0274815
