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AT-hook DNA-binding motif-containing protein one knockdown downregulates EWS-FLI1 transcriptional ac...

AT-hook DNA-binding motif-containing protein one knockdown downregulates EWS-FLI1 transcriptional ac...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2721229237

AT-hook DNA-binding motif-containing protein one knockdown downregulates EWS-FLI1 transcriptional activity in Ewing’s sarcoma cells

About this item

Full title

AT-hook DNA-binding motif-containing protein one knockdown downregulates EWS-FLI1 transcriptional activity in Ewing’s sarcoma cells

Publisher

San Francisco: Public Library of Science

Journal title

PloS one, 2022-10, Vol.17 (10), p.e0269077-e0269077

Language

English

Formats

Publication information

Publisher

San Francisco: Public Library of Science

More information

Scope and Contents

Contents

Ewing’s sarcoma is the second most common bone malignancy in children or young adults and is caused by an oncogenic transcription factor by a chromosomal translocation between the EWSR1 gene and the ETS transcription factor family. However, the transcriptional mechanism of EWS-ETS fusion proteins is still unclear. To identify the transcriptional co...

Alternative Titles

Full title

AT-hook DNA-binding motif-containing protein one knockdown downregulates EWS-FLI1 transcriptional activity in Ewing’s sarcoma cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2721229237

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2721229237

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0269077

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