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Feasibility of a novel non-invasive swab technique for serial whole-exome sequencing of cervical tum...

Feasibility of a novel non-invasive swab technique for serial whole-exome sequencing of cervical tum...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2722285203

Feasibility of a novel non-invasive swab technique for serial whole-exome sequencing of cervical tumors during chemoradiation therapy

About this item

Full title

Feasibility of a novel non-invasive swab technique for serial whole-exome sequencing of cervical tumors during chemoradiation therapy

Publisher

San Francisco: Public Library of Science

Journal title

PloS one, 2022-10, Vol.17 (10), p.e0274457-e0274457

Language

English

Formats

Publication information

Publisher

San Francisco: Public Library of Science

More information

Scope and Contents

Contents

Background Clinically relevant genetic predictors of radiation response for cervical cancer are understudied due to the morbidity of repeat invasive biopsies required to obtain genetic material. Thus, we aimed to demonstrate the feasibility of a novel noninvasive cervical swab technique to (1) collect tumor DNA with adequate throughput to (2) perfo...

Alternative Titles

Full title

Feasibility of a novel non-invasive swab technique for serial whole-exome sequencing of cervical tumors during chemoradiation therapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2722285203

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2722285203

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0274457

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