Identifying enhancer properties associated with genetic risk for complex traits using regulome-wide...
Identifying enhancer properties associated with genetic risk for complex traits using regulome-wide association studies
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Genetic risk for complex traits is strongly enriched in non-coding genomic regions involved in gene regulation, especially enhancers. However, we lack adequate tools to connect the characteristics of these disruptions to genetic risk. Here, we propose RWAS (Regulome Wide Association Study), a new application of the MAGMA software package to identif...
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Identifying enhancer properties associated with genetic risk for complex traits using regulome-wide association studies
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TN_cdi_plos_journals_2725284602
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2725284602
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ISSN
1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1010430