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Cross-GWAS coherence test at the gene and pathway level

Cross-GWAS coherence test at the gene and pathway level

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2725291180

Cross-GWAS coherence test at the gene and pathway level

About this item

Full title

Cross-GWAS coherence test at the gene and pathway level

Author / Creator

Publisher

San Francisco: Public Library of Science

Journal title

PLoS computational biology, 2022-09, Vol.18 (9), p.e1010517-e1010517

Language

English

Formats

Publication information

Publisher

San Francisco: Public Library of Science

More information

Scope and Contents

Contents

Proximal genetic variants are frequently correlated, implying that the corresponding effect sizes detected by genome-wide association studies (GWAS) are also not independent. Methods already exist to account for this when aggregating effects from a single GWAS across genes or pathways. Here we present a rigorous yet fast method for detecting genes...

Alternative Titles

Full title

Cross-GWAS coherence test at the gene and pathway level

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2725291180

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2725291180

Other Identifiers

ISSN

1553-7358,1553-734X

E-ISSN

1553-7358

DOI

10.1371/journal.pcbi.1010517

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