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Collagen cross-links scale with passive stiffness in dystrophic mouse muscles, but are not altered w...

Collagen cross-links scale with passive stiffness in dystrophic mouse muscles, but are not altered w...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2729490352

Collagen cross-links scale with passive stiffness in dystrophic mouse muscles, but are not altered with administration of a lysyl oxidase inhibitor

About this item

Full title

Collagen cross-links scale with passive stiffness in dystrophic mouse muscles, but are not altered with administration of a lysyl oxidase inhibitor

Publisher

United States: Public Library of Science

Journal title

PloS one, 2022-10, Vol.17 (10), p.e0271776-e0271776

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

In Duchenne muscular dystrophy (DMD), a lack of functional dystrophin leads to myofiber instability and progressive muscle damage that results in fibrosis. While fibrosis is primarily characterized by an accumulation of extracellular matrix (ECM) components, there are changes in ECM architecture during fibrosis that relate more closely to functiona...

Alternative Titles

Full title

Collagen cross-links scale with passive stiffness in dystrophic mouse muscles, but are not altered with administration of a lysyl oxidase inhibitor

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2729490352

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2729490352

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0271776

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