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DR4/DQ2 haplotype confers susceptibility to T1DM with early clinical disease onset: A retrospective...

DR4/DQ2 haplotype confers susceptibility to T1DM with early clinical disease onset: A retrospective...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2738407747

DR4/DQ2 haplotype confers susceptibility to T1DM with early clinical disease onset: A retrospective analysis in a tertiary-care hospital in Italy

About this item

Full title

DR4/DQ2 haplotype confers susceptibility to T1DM with early clinical disease onset: A retrospective analysis in a tertiary-care hospital in Italy

Publisher

United States: Public Library of Science

Journal title

PloS one, 2022-11, Vol.17 (11), p.e0276896

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

T1DM is the most frequent form of diabetes in children. It has a multifactorial pathogenesis in which genetic, environmental and immunological factors are involved. Among genetic explanations a major role is attributed to second class HLA genes, with the greatest risk associated with the simultaneous presence of the haplotypes DR3DQ2 and DR4DQ8. Ba...

Alternative Titles

Full title

DR4/DQ2 haplotype confers susceptibility to T1DM with early clinical disease onset: A retrospective analysis in a tertiary-care hospital in Italy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2738407747

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2738407747

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0276896

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