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Genetic risk scores and dementia risk across different ethnic groups in UK Biobank

Genetic risk scores and dementia risk across different ethnic groups in UK Biobank

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2747881980

Genetic risk scores and dementia risk across different ethnic groups in UK Biobank

About this item

Full title

Genetic risk scores and dementia risk across different ethnic groups in UK Biobank

Publisher

United States: Public Library of Science

Journal title

PloS one, 2022-12, Vol.17 (12), p.e0277378-e0277378

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Genetic Risk Scores (GRS) for predicting dementia risk have mostly been used in people of European ancestry with limited testing in other ancestry groups.
We conducted a logistic regression with all-cause dementia as the outcome and z-standardised GRS as the exposure across diverse ethnic groups.
There was variation in frequency of APOE allel...

Alternative Titles

Full title

Genetic risk scores and dementia risk across different ethnic groups in UK Biobank

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2747881980

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2747881980

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0277378

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