Obeticholic acid treatment ameliorates the cardiac dysfunction in NASH mice
Obeticholic acid treatment ameliorates the cardiac dysfunction in NASH mice
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Suppression of cardiac iinflammasome, which can be inhibited by Farnesoid X receptor (FXR) agonist, can ameliorate cardiac inflammation and fibrosis. Increased cardiac inflammasome decrease the abundance of regulatory T (Treg) cells and exacerbate cardiac dysfunction. Interaction between cardiomyocytes and Treg cells is involved in the development...
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Full title
Obeticholic acid treatment ameliorates the cardiac dysfunction in NASH mice
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TN_cdi_plos_journals_2748823390
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2748823390
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0276717
