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Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance f...

Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance f...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2762198696

Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

A hallmark of
Listeria (L
.
) monocytogenes
pathogenesis is bacterial escape from maturing entry vacuoles, which is required for rapid bacterial replication in the host cell cytoplasm and cell-to-cell spread. The bacterial transcriptional activator PrfA controls expression of key virulence factors that enable exploitation of this intrac...

Alternative Titles

Full title

Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2762198696

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2762198696

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1010166