LOF variants identifying candidate genes of laterality defects patients with congenital heart diseas...
LOF variants identifying candidate genes of laterality defects patients with congenital heart disease
About this item
Full title
Author / Creator
Liu, Sijie , Wei, Wei , Wang, Pengcheng , Liu, Chunjie , Jiang, Xuechao , Li, Tingting , Li, Fen , Wu, Yurong , Chen, Sun , Sun, Kun and Xu, Rang
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Defects in laterality pattern can result in abnormal positioning of the internal organs during the early stages of embryogenesis, as manifested in heterotaxy syndrome and situs inversus, while laterality defects account for 3~7% of all congenital heart defects (CHDs). However, the pathogenic mechanism underlying most laterality defects remains unkn...
Alternative Titles
Full title
LOF variants identifying candidate genes of laterality defects patients with congenital heart disease
Authors, Artists and Contributors
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Record Identifier
TN_cdi_plos_journals_2766098380
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2766098380
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1010530
