Loss of growth differentiation factor 9 causes an arrest of early folliculogenesis in zebrafish–A no...
Loss of growth differentiation factor 9 causes an arrest of early folliculogenesis in zebrafish–A novel insight into its action mechanism
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Author / Creator
Chen, Weiting , Zhai, Yue , Zhu, Bo , Wu, Kun , Fan, Yuqin , Zhou, Xianqing , Liu, Lin and Ge, Wei
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Growth differentiation factor 9 (GDF9) was the first oocyte-specific growth factor identified; however, most information about GDF9 functions comes from studies in the mouse model. In this study, we created a mutant for Gdf9 gene (
gdf9-/-
) in zebrafish using TALEN approach. The loss of Gdf9 caused a complete arrest of follicle development a...
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Full title
Loss of growth differentiation factor 9 causes an arrest of early folliculogenesis in zebrafish–A novel insight into its action mechanism
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TN_cdi_plos_journals_2766098424
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2766098424
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1010318