Heterozygous deletion of Gpr55 does not affect a hyperthermia-induced seizure, spontaneous seizures...
Heterozygous deletion of Gpr55 does not affect a hyperthermia-induced seizure, spontaneous seizures or survival in the Scn1a+/- mouse model of Dravet syndrome
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
A purified preparation of cannabidiol (CBD), a cannabis constituent, has been approved for the treatment of intractable childhood epilepsies such as Dravet syndrome. Extensive pharmacological characterization of CBD shows activity at numerous molecular targets but its anticonvulsant mechanism(s) of action is yet to be delineated. Many suggest that...
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Full title
Heterozygous deletion of Gpr55 does not affect a hyperthermia-induced seizure, spontaneous seizures or survival in the Scn1a+/- mouse model of Dravet syndrome
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TN_cdi_plos_journals_2769975481
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2769975481
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0280842
