Detection of BRAF mutations in malignant melanoma and colorectal cancer by SensiScreen® FFPE BRAF qP...
Detection of BRAF mutations in malignant melanoma and colorectal cancer by SensiScreen® FFPE BRAF qPCR assay
About this item
Full title
Author / Creator
Sørensen, Anna Lahn , Guldmann-Christensen, Mariann , Børgesen, Michael , Petersen, Rasmus Koefoed , Flugt, Katharina , Duelund, Julie Mejer Holmgaard , Kyneb, Majbritt Hauge , Lorenzen, Jan , Pipó-Ollé, Emma , Epistolio, Samantha , Riva, Alice , Dazio, Giulia , Merlo, Elisabetta , Meyer, Tine , Christensen, Ulf Bech and Frattini, Milo
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Mutations in
BRAF
exon 15 lead to conformational changes in its activation loops, resulting in constitutively active BRAF proteins which are implicated in the development of several human cancer types. Different BRAF inhibitors have been developed and introduced in clinical practice. Identification of
BRAF
mutations influences the clini...
Alternative Titles
Full title
Detection of BRAF mutations in malignant melanoma and colorectal cancer by SensiScreen® FFPE BRAF qPCR assay
Authors, Artists and Contributors
Author / Creator
Guldmann-Christensen, Mariann
Børgesen, Michael
Petersen, Rasmus Koefoed
Flugt, Katharina
Duelund, Julie Mejer Holmgaard
Kyneb, Majbritt Hauge
Lorenzen, Jan
Pipó-Ollé, Emma
Epistolio, Samantha
Riva, Alice
Dazio, Giulia
Merlo, Elisabetta
Meyer, Tine
Christensen, Ulf Bech
Frattini, Milo
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2774826041
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2774826041
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0281558
