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Targeted proteomics using stable isotope labeled protein fragments enables precise and robust determ...

Targeted proteomics using stable isotope labeled protein fragments enables precise and robust determ...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2776986760

Targeted proteomics using stable isotope labeled protein fragments enables precise and robust determination of total apolipoprotein(a) in human plasma

About this item

Full title

Targeted proteomics using stable isotope labeled protein fragments enables precise and robust determination of total apolipoprotein(a) in human plasma

Publisher

United States: Public Library of Science

Journal title

PloS one, 2023-02, Vol.18 (2), p.e0281772-e0281772

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Lipoprotein(a), also known as Lp(a), is an LDL-like particle composed of apolipoprotein(a) (apo(a)) bound covalently to apolipoprotein B100. Plasma concentrations of Lp(a) are highly heritable and vary widely between individuals. Elevated plasma concentration of Lp(a) is considered as an independent, causal risk factor of cardiovascular disease (CV...

Alternative Titles

Full title

Targeted proteomics using stable isotope labeled protein fragments enables precise and robust determination of total apolipoprotein(a) in human plasma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2776986760

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2776986760

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0281772

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