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Identification of cancer-related genes FGFR2 and CEBPB in choledochal cyst via RNA sequencing of pat...

Identification of cancer-related genes FGFR2 and CEBPB in choledochal cyst via RNA sequencing of pat...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2792881856

Identification of cancer-related genes FGFR2 and CEBPB in choledochal cyst via RNA sequencing of patient-derived liver organoids

About this item

Full title

Identification of cancer-related genes FGFR2 and CEBPB in choledochal cyst via RNA sequencing of patient-derived liver organoids

Publisher

United States: Public Library of Science

Journal title

PloS one, 2023-03, Vol.18 (3), p.e0283737-e0283737

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Choledochal cysts (CC) are congenital bile duct anomalies with 6-30% risk for developing bile duct cancer. However, the molecular mechanisms underlying cancer risk of CC are unknown. We sought to identify the gene expression changes underlying the cancer risk of CC patients.
Liver organoids (n = 51) were generated from liver/bile duct biopsies o...

Alternative Titles

Full title

Identification of cancer-related genes FGFR2 and CEBPB in choledochal cyst via RNA sequencing of patient-derived liver organoids

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2792881856

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2792881856

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0283737

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