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Putrescine supplementation shifts macrophage L-arginine metabolism related-genes reducing Leishmania...

Putrescine supplementation shifts macrophage L-arginine metabolism related-genes reducing Leishmania...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2793381500

Putrescine supplementation shifts macrophage L-arginine metabolism related-genes reducing Leishmania amazonensis infection

About this item

Full title

Putrescine supplementation shifts macrophage L-arginine metabolism related-genes reducing Leishmania amazonensis infection

Publisher

United States: Public Library of Science

Journal title

PloS one, 2023-03, Vol.18 (3), p.e0283696-e0283696

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Leishmania is a protozoan that causes leishmaniasis, a neglected tropical disease with clinical manifestations classified as cutaneous, mucocutaneous, and visceral leishmaniasis. In the infection context, the parasite can modulate macrophage gene expression affecting the microbicidal activity and immune response. The metabolism of L-arginine into p...

Alternative Titles

Full title

Putrescine supplementation shifts macrophage L-arginine metabolism related-genes reducing Leishmania amazonensis infection

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2793381500

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2793381500

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0283696

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