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Hierarchical association of COPD to principal genetic components of biological systems

Hierarchical association of COPD to principal genetic components of biological systems

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2819261052

Hierarchical association of COPD to principal genetic components of biological systems

About this item

Full title

Hierarchical association of COPD to principal genetic components of biological systems

Publisher

United States: Public Library of Science

Journal title

PloS one, 2023-05, Vol.18 (5), p.e0286064-e0286064

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Many disease-causing genetic variants converge on common biological functions and pathways. Precisely how to incorporate pathway knowledge in genetic association studies is not yet clear, however. Previous approaches employ a two-step approach, in which a regular association test is first performed to identify variants associated with the disease p...

Alternative Titles

Full title

Hierarchical association of COPD to principal genetic components of biological systems

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2819261052

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2819261052

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0286064

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