Production of the antidepressant orcinol glucoside in Yarrowia lipolytica with yields over 6,400-fol...
Production of the antidepressant orcinol glucoside in Yarrowia lipolytica with yields over 6,400-fold higher than plant extraction
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Author / Creator
Chen, Bihuan , Liu, Xiaonan , Wang, Yina , Bai, Jie , Liu, Xiangyu , Xiang, Guisheng , Liu, Wei , Zhu, Xiaoxi , Cheng, Jian , Lu, Lina , Zhang, Guanghui , Zhang, Ge , Dai, Zongjie , Zi, Shuhui , Yang, Shengchao and Jiang, Huifeng
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Contents
Orcinol glucoside (OG), mainly found in the rhizome of the traditional Chinese herb
Curculigo orchioides
Gaertn, is noted for its antidepressant effects. In this study, an efficient screening pipeline was established for identifying the highly active orcinol synthase (ORS) and UDP-dependent glycosyltransferase (UGT) involved in the biosynthes...
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Full title
Production of the antidepressant orcinol glucoside in Yarrowia lipolytica with yields over 6,400-fold higher than plant extraction
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TN_cdi_plos_journals_2838338029
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2838338029
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ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.3002131
