Optimization of differentiation and transcriptomic profile of THP-1 cells into macrophage by PMA
Optimization of differentiation and transcriptomic profile of THP-1 cells into macrophage by PMA
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Author / Creator
Liu, Tiezhu , Huang, Tao , Li, Jiajia , Li, Aqian , Li, Chuan , Huang, Xiaoxia , Li, Dexin , Wang, Shiwen and Liang, Mifang
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
THP-1 monocyte, which can be differentiated into macrophages by PMA, is widely used in researches on pathogen infection and host innate immunity, but reports on the induction methods of PMA are different and lack a unified standard, and the transcriptome characteristics of macrophage compared with THP-1 cells remains unclear. In this research, we e...
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Full title
Optimization of differentiation and transcriptomic profile of THP-1 cells into macrophage by PMA
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Record Identifier
TN_cdi_plos_journals_2838634393
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2838634393
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0286056
