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Fusogenic structural changes in arenavirus glycoproteins are associated with viroporin activity

Fusogenic structural changes in arenavirus glycoproteins are associated with viroporin activity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2851952697

Fusogenic structural changes in arenavirus glycoproteins are associated with viroporin activity

About this item

Full title

Fusogenic structural changes in arenavirus glycoproteins are associated with viroporin activity

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2023-07, Vol.19 (7), p.e1011217-e1011217

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Many enveloped viruses enter host cells by fusing with acidic endosomes. The fusion activity of multiple viral envelope glycoproteins does not generally affect viral membrane permeability. However, fusion induced by the Lassa virus (LASV) glycoprotein complex (GPc) is always preceded by an increase in viral membrane permeability and the ensuing aci...

Alternative Titles

Full title

Fusogenic structural changes in arenavirus glycoproteins are associated with viroporin activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2851952697

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2851952697

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1011217

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