A previously unrecognized superfamily of macro-conotoxins includes an inhibitor of the sensory neuro...
A previously unrecognized superfamily of macro-conotoxins includes an inhibitor of the sensory neuron calcium channel Cav2.3
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Author / Creator
Hackney, Celeste M , Flórez Salcedo, Paula , Mueller, Emilie , Koch, Thomas Lund , Kjelgaard, Lau D , Watkins, Maren , Zachariassen, Linda G , Tuelung, Pernille Sønderby , McArthur, Jeffrey R , Adams, David J , Kristensen, Anders S , Olivera, Baldomero , Finol-Urdaneta, Rocio K , Safavi-Hemami, Helena , Morth, Jens Preben and Ellgaard, Lars
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Animal venom peptides represent valuable compounds for biomedical exploration. The venoms of marine cone snails constitute a particularly rich source of peptide toxins, known as conotoxins. Here, we identify the sequence of an unusually large conotoxin, Mu8.1, which defines a new class of conotoxins evolutionarily related to the well-known con-ikot...
Alternative Titles
Full title
A previously unrecognized superfamily of macro-conotoxins includes an inhibitor of the sensory neuron calcium channel Cav2.3
Authors, Artists and Contributors
Author / Creator
Flórez Salcedo, Paula
Mueller, Emilie
Koch, Thomas Lund
Kjelgaard, Lau D
Watkins, Maren
Zachariassen, Linda G
Tuelung, Pernille Sønderby
McArthur, Jeffrey R
Adams, David J
Kristensen, Anders S
Olivera, Baldomero
Finol-Urdaneta, Rocio K
Safavi-Hemami, Helena
Morth, Jens Preben
Ellgaard, Lars
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2865506127
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2865506127
Other Identifiers
ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.3002217