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Immunomodulatory and pro-oncologic effects of ketamine and isoflurane anesthetics in a murine model

Immunomodulatory and pro-oncologic effects of ketamine and isoflurane anesthetics in a murine model

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2875359335

Immunomodulatory and pro-oncologic effects of ketamine and isoflurane anesthetics in a murine model

About this item

Full title

Immunomodulatory and pro-oncologic effects of ketamine and isoflurane anesthetics in a murine model

Publisher

United States: Public Library of Science

Journal title

PloS one, 2023-10, Vol.18 (10), p.e0292492-e0292492

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Volatile and intravenous anesthetics may worsen oncologic outcomes in basic science animal models. These effects may be related to suppressed innate and adaptive immunity, decreased immunosurveillance, and disrupted cellular signaling. We hypothesized that anesthetics would promote lung tumor growth via altered immune function in a murine model and...

Alternative Titles

Full title

Immunomodulatory and pro-oncologic effects of ketamine and isoflurane anesthetics in a murine model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2875359335

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2875359335

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0292492

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