Allosteric inhibition of muscle-type nicotinic acetylcholine receptors by a neuromuscular blocking a...
Allosteric inhibition of muscle-type nicotinic acetylcholine receptors by a neuromuscular blocking agent pancuronium
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Publisher
San Francisco: Public Library of Science
Journal title
Language
English
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Publisher
San Francisco: Public Library of Science
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Contents
Muscle relaxants are indispensable for surgical anesthesia. Early studies suggested that a classical non-depolarizing muscle relaxant pancuronium competitively binds to the ligand binding site to block nicotinic acetylcholine receptors (nAChR). Our group recently showed that nAChR which has two distinct subunit combinations are expressed in zebrafi...
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Full title
Allosteric inhibition of muscle-type nicotinic acetylcholine receptors by a neuromuscular blocking agent pancuronium
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TN_cdi_plos_journals_2876423576
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2876423576
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0292262
