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Systematic characterization of all Toxoplasma gondii TBC domain-containing proteins identifies an es...

Systematic characterization of all Toxoplasma gondii TBC domain-containing proteins identifies an es...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069178341

Systematic characterization of all Toxoplasma gondii TBC domain-containing proteins identifies an essential regulator of Rab2 in the secretory pathway

About this item

Full title

Systematic characterization of all Toxoplasma gondii TBC domain-containing proteins identifies an essential regulator of Rab2 in the secretory pathway

Publisher

United States: Public Library of Science

Journal title

PLoS biology, 2024-05, Vol.22 (5), p.e3002634

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Toxoplasma gondii resides in its intracellular niche by employing a series of specialized secretory organelles that play roles in invasion, host cell manipulation, and parasite replication. Rab GTPases are major regulators of the parasite's secretory traffic that function as nucleotide-dependent molecular switches to control vesicle trafficking. Wh...

Alternative Titles

Full title

Systematic characterization of all Toxoplasma gondii TBC domain-containing proteins identifies an essential regulator of Rab2 in the secretory pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_3069178341

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069178341

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.3002634

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