A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in hum...
A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection
About this item
Full title
Author / Creator
Maure, Alexandra , Lawarée, Emeline , Fiorentino, Francesco , Pawlik, Alexandre , Gona, Saideep , Giraud-Gatineau, Alexandre , Eldridge, Matthew J. G. , Danckaert, Anne , Hardy, David , Frigui, Wafa , Keck, Camille , Gutierrez, Claude , Neyrolles, Olivier , Aulner, Nathalie , Mai, Antonello , Hamon, Mélanie , Barreiro, Luis B. , Brodin, Priscille , Brosch, Roland , Rotili, Dante and Tailleux, Ludovic
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Antituberculosis drugs, mostly developed over 60 years ago, combined with a poorly effective vaccine, have failed to eradicate tuberculosis. More worryingly, multiresistant strains of
Mycobacterium tuberculosis
(MTB) are constantly emerging. Innovative strategies are thus urgently needed to improve tuberculosis treatment. Recently, host-direc...
Alternative Titles
Full title
A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection
Authors, Artists and Contributors
Author / Creator
Lawarée, Emeline
Fiorentino, Francesco
Pawlik, Alexandre
Gona, Saideep
Giraud-Gatineau, Alexandre
Eldridge, Matthew J. G.
Danckaert, Anne
Hardy, David
Frigui, Wafa
Keck, Camille
Gutierrez, Claude
Neyrolles, Olivier
Aulner, Nathalie
Mai, Antonello
Hamon, Mélanie
Barreiro, Luis B.
Brodin, Priscille
Brosch, Roland
Rotili, Dante
Tailleux, Ludovic
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_3069178367
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069178367
Other Identifiers
ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.3002259
